may also be extracted from individual worms after manual correction. Measurements, such as intensity of stain, fat stain distribution, fat region size, worm width etc. due to a different image resolution or different worm strain), a new worm model can be created using Pipeline 2 (pink) to (g) manually select non-touching worms making up a training set for a new model built by Pipeline 3.įor low-throughput experiments, it is possible to manually curate faulty segmentation results using Pipeline 4 (orange) by (h) manual editing of the output from step d of pipeline 1, and (i) manual flipping of digitally straightened worms so that they all align in with heads or tails up.
If the provided default worm model does not fit the input data (e.g. Once worms and fatty regions are identified, a large number of intensity, shape and texture measurements are extracted. Now, each individual detected worm has a unique color.ĭigitally straighten worms and align them to a simple worm atlas for measurement of stain distribution.ĭetect fatty regions within worms. Individual worms/worm clusters are randomly colored.ĭelineate individual worms by model-based worm untangling. Pre-process to detect artifacts such as bubbles and well edges.ĭetect worms and clusters of worms. This game will bring you joy and twist your brain at the same time.The main analysis pipeline, Pipeline 1, shown in blue, is fully automated, and consists of the following steps: Worm Frenzy: Hungry Snake is a fun and free game. Try hard to pass through all levels because our game is not as simple as it seems. If you want to win, collect fruits to make the hungry worm reach its full length. Think logically, correctly calculate your move, and collect all the fruits, but be careful, because many unexpected straps are waiting for you. How to help the worm seek the apples in the dangerous maze?
Move hungry worm, avoid dangers, collect fruits, and run away from the maze.Ī hungry worm is frenzy seeking fruits to eat.
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